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Notably, several genes, such as NAD(P)H dehydrogenase [quinone] 1 (NQO1), aldo-keto reductase family 1 member C3 (AKR1C3), and glutathione peroxidase 2 (GPX2), identified through gene expression dataset analysis, have been implicated in ferroptosis and exhibit promising diagnostic potential [109]

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PKC activation reduces amiloride-sensitive epithelial sodium channel (ENaC) expression, which is important for alveolar fluid clearance (AFC) and results in enhanced lung edema and worsened lung function [47]