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Cognitive issues often include concentration and memory difficulties, with around 64.5% of users reporting emotional numbness and dulling, according to Mattingly G, et al 2016 study titled, The Impact of Cognitive Challenges in Major Depression published in the Postgraduate Medicine

[170] 2016 CDC controversy [edit] In 2016, a CDC press release and infographic entitled "More than 3 million US women at risk for alcohol-exposed pregnancy" caused controversy

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